Depression + fatigue are key psychoneurological symptoms of intensity-modulated radiotherapy for patients with HeadandNeckCancer. MedTwitter
These core IMRT-related issues often co-occur, or cluster, alongside other symptoms, including sleep trouble, pain, and cognitive dysfunction, and this interconnectedness may make it possible to manage the network of symptoms, a new analysis finds.
To understand these associations better, Lin and colleagues used a network analysis to identify relationships between depression, fatigue, sleep trouble, pain, and cognitive dysfunction, the five most common and distressing psychoneurological symptoms reported by patients with head and neck cancer undergoing IMRT.
Fatigue was the most prevalent symptom, reported by 54% to 75% of patients across the time points, but related to three, not all four, of the other core psychoneurological symptoms. at T1, T3, and T4, depression and fatigue at T2, T3, and T4, and depression and cognitive dysfunction at T4.were also associated with stronger symptom networks.
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