Researchers have found long-term evidence that actively monitoring localized prostate cancer is a safe alternative to immediate surgery or radiation.
The results, released Saturday, are encouraging for men who want to avoid treatment-related sexual and incontinence problems, said Dr. Stacy Loeb, a prostate cancer specialist at NYU Langone Health who was not involved in the research.
"There was no difference in prostate cancer mortality at 15 years between the groups," Loeb said. And prostate cancer survival for all three groups was high — 97% regardless of treatment approach."That's also very good news." Men diagnosed with localized prostate cancer shouldn't panic or rush treatment decisions, said lead author Dr. Freddie Hamdy of the University of Oxford. Instead, they should"consider carefully the possible benefits and harms caused by the treatment options."Researchers followed more than 1,600 U.K. men who agreed to be randomly assigned to get surgery, radiation or active monitoring.
At 15 years, cancer had spread in 9.4% of the active-monitoring group, 4.7% of the surgery group and 5% of the radiation group. The study was started in 1999, and experts said today's monitoring practices are better, with MRI imaging and gene tests guiding decisions.
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