University of Chicago researchers discover crucial protein for cellular function
CHICAGO -- Lysosomes – membrane-bound structures found in every cell – are sometimes known as the cells' 'garbage disposals' or 'cellular janitors.' The structures are full of enzymes that can break down all different substances – including proteins, nucleic acids, carbohydrates, and lipids – so their components can be recycled.
'Part of the problem has been an inability to measure calcium inside the lysosome,' Matthew Zajac, the first author of the paper on the study, said in a UChicago news release. 'Because it's a highly acidic compartment, it's been hard to measure the calcium without that acidity interfering with measurements.
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