Unlocking Nature’s Secret: How Two Ferredoxins Fuel the Future of Fertilizers

Science, Space and Technology News 2024

It has recently been shown that the biocatalyst iron nitrogenase not only fixes nitrogen, but also carbon dioxide. However, this nitrogenase form has so far been the least studied. Now two proteins have been identified that are crucial for the energy supply of the enzyme. Credit: Max Planck Institute for Terrestrial Microbiology/Geisel

Nitrogenases are considered promising candidates for the sustainable enzymatic production of ammonia and carbon compounds. Unfortunately, one bottleneck in this complex process, the supply of electrons to the enzymes, has remained a mystery until now.

Enzymatically and sustainably produced fertilizers could save around one percent of the energy consumed globally and the associated carbon dioxide released, which is why many research labs and start-ups are focusing on the topic. However, nitrogenase research is challenging because nitrogenases are a highly complex metalloenzymes and many aspects of their reactivity and catalysis are still poorly understood.

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