More people will have access to a new treatment for Alzheimer’s — thanks to a University of Washington (UW) study called AHEAD.
, is the first traditionally-approved treatment that addresses the underlying biology of Alzheimer’s and changes the course of the disease in a meaningful way for people in the early stages.
“It’s been over 20 years since the last Alzheimer’s drug was approved by the FDA so this is a really exciting moment,” UW Medicine behavioral neurologist Michael Rosenbloom, M.D. told KIRO Newsradio. Lecanemab slowed participants’ cognitive and functional decline by 27% over the course of 18 months during Clarity AD trials, Rosenbloom said, adding that the drug’s longer-term effectiveness is not well understood.
“When you see multiple drugs of the same class meeting the primary outcome measures, this shows that this is not a fluke. We have a real disease-modifying agent that is beneficial for patients,” Rosenbloom said in a prepared statement. “When I became a behavioral neurologist over 13 years ago, the idea of having a disease-modifying drug sounded like science fiction.”The AHEAD study will further measure and monitor the influence of Lecanemab.
“For the first time, we have a drug that is approved for Alzheimer’s disease that is developed to be disease-modifying and actually met its primary outcome measures,” Rosenbloom said.
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