Understanding the root causes of menopause could have a profound effect on not just understanding female health, but also decoding the process of human aging. Via WiredUK 📸: Cavan Images/Getty Images
However, menopause not only has a profound effect on fertility, it also deeply affects women’s overall health. “After menopause, a woman has a fourfold increased risk of cardiovascular disease,” Garrison says. “Risks for diseases like osteoporosis, cognitive decline, arthritis, and autoimmune disease—they all go up.”
Understanding the root causes, however, could have a profound effect on not just understanding female health, but also. “Ovaries are the canary in the coal mine for aging.” Garrison says. “Understanding what is driving ovarian aging will give us clues about aging in the rest of the body.” Lack of research funding into reproductive aging is compounded by systematic biases that still affect biological and medical research. According to Garrison, only in 2016 did the NIH mandate that clinical studies include female animals as well as male. “The male body really has been biology’s baseline,” Garrison says. “That means that we have basically a century of preclinical data which was conducted and collected only in males.
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