Science has long protected pregnant women from research. Now researchers say it’s time to protect them *through* research.
Until clinical trials during pregnancy become more routine, pregnant people face an untenable choice — take a drug without knowing its safety, or leave their medical conditions untreated.Nature Reviews Endocrinology
Acetaminophen is an active ingredient in more than 600 medications, including Tylenol, and is estimated to be used by up to 65 percent of pregnant people in the United States. It has long been the preferred pain medication and fever reducer during pregnancy because the— such as ibuprofen and aspirin — in the second half of pregnancy. Those drugs have been linked to rare fetal kidney problems and low amniotic fluid levels.
“We’re looking at subtle effects here,” Swan says, “but that doesn’t mean that they’re not important.” With such widespread use, “there’s a good chance that a fair number of offspring are affected.”
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