Some older athletes may owe their high performance to their mitochondria.
In 2011, Fauja Singh became the oldest person to run a marathon when he completed all 42 kilometers of a Toronto race in just over 8 hours. Singh—100 at the time —is exceptional, but he’s not alone. People train and compete in athletic events well into their 70s, 80s, and 90s.
He and his colleagues also reached out to senior world-record holders, eventually recruiting 15 senior athletes, all about 80 years old. Half competed in sprint events, half competed in endurance races, and several were best in the world for their event and age categories. Many of these proteins were produced at higher levels, but some were actually reduced. The athlete’s muscle cells made fewer proteins involved with a cellular structure called the spliceosome, for example, which helps buffer a typical cell from some effects of aging. It’s more proof that their cells aren’t aging like the rest of ours, says Luigi Ferrucci, a geriatrician at the National Institutes of Health’s National Institute on Aging and an author of the study.
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