Science, Space and Technology News 2024
A new study by Yale scientists has identified a specific brain region that may cause paranoia by comparing behavioral data from monkeys and humans. This research utilized a novel approach, aligning animal and human studies using a computational model to analyze how participants perceive environmental stability and adapt to changes.
If the participants selected the option with the highest probability of reward, they would get a reward with fewer clicks across trials. The option with the lowest probability required more clicks to receive a reward. The third option, meanwhile, was somewhere in the middle. Participants did not have information on the reward probability and had to uncover their best option by trial and error.
“So participants have to figure out what’s the best target, and when there’s a perceived change in the environment, the participant then has to find the new best target,” said Steve Chang, associate professor of psychology and of neuroscience in Yale’s Faculty of Arts and Sciences and co-senior author of the study.
The researchers found that the presence of lesions in both brain regions negatively affected the behavior of the monkeys, but in different ways.
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