A study by Tulane University reveals that frequent illness may accelerate brain aging and increase the risk of dementia or cognitive decline. The findings highlight the importance of maintaining good health to prevent infections, especially among the elderly and dementia-prone individuals. Gettin
Researchers discovered a link between frequent illness and accelerated brain aging, increasing the risk of dementia or cognitive decline. The study, published in, used aging male mice and found that repeated, moderate inflammation from infections like the flu or seasonal colds led to impaired cognition and disrupted neuronal communication.
“We were interested in asking whether differences in infection experience could account, at least in part, for the differences in rates of dementia we see in the population,” said lead author Elizabeth Engler-Chiurazzi, PhD, a behavioral neuroscientist in the Tulane Department of Neurosurgery. “The mice we were studying were adults approaching middle age that had intact faculties, and yet, when exposed to intermittent inflammation, they remembered less and their neurons functioned more poorly.
Humans often experience infections and inflammation at substantially higher rates than laboratory mice. But given that impairments were observed in mice after only five intermittent inflammatory treatments, the cognitive change in humans may be more robust.
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