Immune therapy tweak offers new hope to blood cancer patients

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Immune therapy tweak offers new hope to blood cancer patients
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In a small trial, a modified form of a cancer treatment had fewer side effects.

“Natural killer cells are the best killers of virally infected and abnormal cells,” she said. “They can continue to patrol and recognize abnormal cells.”

Presumably, this would cut down on the wait time and the costs of the therapy, because the treatments weren’t being tailor-made for each individual patient.Rezvani and her colleagues genetically modified the natural killer cells to have a receptor for a protein that is on the surface of the cancer cells they were targeting. The receptor would lock onto the protein and then the cell would do its work.

Rezvani and her colleagues tested the new treatment in 11 blood cancer patients. When the patients were checked two months after treatment, seven had no signs of cancer while one other showed improvement but not complete remission. The other three had no response to the treatment.“I didn’t have any other options,” Cox, who received the treatment for non-Hodgkin lymphoma, said. “But it was scary knowing I would be No. 8 and would be getting the biggest dose.

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